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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight-loss in addition to a reduced-calorie diet and physical activity.
Using two separate drugs to shed weight can be very effective you'll find combinations as you're watching FDA now awaiting approval. When dealing with fat loss and the people who go through it one should err along the side of caution and let the FDA do its job and demand some study be done so that the public is aware of the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies have been in business to earn money and that they would say almost anything to keep people on their medications.
Researchers found out that participants taking this drug for a year, dropped a few pounds within four weeks and have kept the body weight off throughout the 56 weeks with the study. Contrave can be a combination with the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which might be made up of multiple active ingredient, which can make them more efficient and safer.
Combo-pilling will be the newest fad or even better the newest ahead under scrutiny and thus it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills has become popular may be the fact that since right now there aren't long term prescription weight loss supplements that have been approved by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be licensed by the FDA.
Seizures really are a side effect with Contrave and must not be taken in those with seizure disorders. The drug can also raise blood pressure levels and heart rate, and must not be used in individuals with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug.
The FDA also warned that Contrave can raise blood pressure and heartrate and must not used in patients with uncontrolled high blood pressure level, in addition to by you are not heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients which has a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients to the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.
From a psychiatric standpoint, evidence suggests that the ordinary neural mechanism for goal-directed behavior continues to be hijacked by the addiction, and malfunctions such that its ordinary functions are exaggerated and fixated on its object. An object produces a stimulus and also the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008).
